Cellfishing is a web-service that predicts the sensitivity of several cell lines with respect to the query compound. The prediction of a cell-line sensitivity to chemical compounds is a very important factor to
optimize in-vitro assays in the drug discovery processes.
The method is based on similarity between queries of compounds and our internal database. It is a direct similarity-based strategy is used in this approach for predictions of compounds-cell lines interactions. The current database comprises 129808 ligand-cell line associations classified as sensible and 950 cell lines.
The output is a table like:
- Col 1: Ordering number
- Col 2: Cell Name as presented in ChemBL database
- Col 3 and Col 4: Links the cell line information in the ChemBL and Cellosaurus databases respectively.